Expression of Nephrin in Pediatric Kidney Diseases
نویسندگان
چکیده
منابع مشابه
Expression of nephrin in pediatric kidney diseases.
Nephrin is a podocyte cell adhesion protein located at the slit diaphragm area of the kidney glomerulus. Mutations in the nephrin gene (NPHS1) lead to congenital nephrosis, suggesting that nephrin is essential for the glomerular filtration barrier. This prompted this study of the expression of nephrin in acquired pediatric kidney diseases using in situ hybridization and immunohistochemistry. In...
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ژورنال
عنوان ژورنال: Journal of the American Society of Nephrology
سال: 2001
ISSN: 1046-6673,1533-3450
DOI: 10.1681/asn.v122289